Distinct effects of AMPAR subunit depletion on spatial memory

Summary: Pharmacological studies established a role for AMPARs in the mammalian forebrain in spatial memory performance. Here we generated global GluA1/3 double knockout mice (Gria1/3−/−) and conditional knockouts lacking GluA1 and GluA3 AMPAR subunits specifically from principal cells across the fo...

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Bibliographic Details
Main Authors: Ahmed Eltokhi, Ilaria Bertocchi, Andrei Rozov, Vidar Jensen, Thilo Borchardt, Amy Taylor, Catia C. Proenca, John Nick P. Rawlins, David M. Bannerman, Rolf Sprengel
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223021934