Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERBα in mice

Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERBα in mice

Puerariae lobatae radix (PLR) is a wildly used herbal medicine. Here we aimed to assess the PLR efficacy against UVB (ultraviolet-B)-induced skin aging and to determine the mechanisms thereof. We found a significant protective effect of PLR (topical application) on UVB-induced skin aging in mice, as...

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Bibliographic Details
Main Authors: Luyao Ma, Meiping Huang, Guanghui Sun, Yanke Lin, Danyi Lu, Baojian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
Puerariae lobatae radix
skin aging
REV-ERBα
BMAL1
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1088294/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1088294/full

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