Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms

Summary: Vertebrates have evolved three paralogs, termed LUC7L, LUC7L2, and LUC7L3, of the essential yeast U1 small nuclear RNA (snRNA)-associated splicing factor Luc7p. We investigated the mechanistic and regulatory functions of these putative splicing factors, of which one (LUC7L2) is mutated or d...

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Prif Awduron: Noah J. Daniels, Courtney E. Hershberger, Xiaorong Gu, Caroline Schueger, William M. DiPasquale, Jonathan Brick, Yogen Saunthararajah, Jaroslaw P. Maciejewski, Richard A. Padgett
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2021-04-01
Cyfres:Cell Reports
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S221112472100303X