Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis

Abstract Two distinct forms of the erythropoietin receptor (EPOR) mediate the cellular responses to erythropoietin (EPO) in different tissues. EPOR homodimers signal to promote the maturation of erythroid progenitor cells. In other cell types, including immune cells, EPOR and the ß-common receptor (...

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Main Authors: Manfred Nairz, David Haschka, Stefanie Dichtl, Thomas Sonnweber, Andrea Schroll, Malte Aßhoff, John E. Mindur, Patrizia L. Moser, Dominik Wolf, Filip K. Swirski, Igor Theurl, Anthony Cerami, Michael Brines, Günter Weiss
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13046-3

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https://doi.org/10.1038/s41598-017-13046-3

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