In-Silico Characterization of Estrogen Reactivating β-Glucuronidase Enzyme in GIT Associated Microbiota of Normal Human and Breast Cancer Patients

In-Silico Characterization of Estrogen Reactivating β-Glucuronidase Enzyme in GIT Associated Microbiota of Normal Human and Breast Cancer Patients

Estrogen circulating in blood has been proved to be a strong biomarker for breast cancer. A β-glucuronidase enzyme (GUS) from human gastrointestinal tract (GIT) microbiota including probiotics has significant involvement in enhancing the estrogen concentration in blood through deconjugation of glucu...

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Bibliographic Details
Main Authors: Fatima Muccee, Shakira Ghazanfar, Wajya Ajmal, Majid Al-Zahrani
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Genes
Subjects:
breast cancer
estrogen
probiotics
<i>Lactobacillus</i>
reactivation
deconjugation
Online Access:https://www.mdpi.com/2073-4425/13/9/1545

Internet

https://www.mdpi.com/2073-4425/13/9/1545

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