A Multicenter Study to Assess EGFR Mutational Status in Plasma: Focus on an Optimized Workflow for Liquid Biopsy in a Clinical Setting

A Multicenter Study to Assess EGFR Mutational Status in Plasma: Focus on an Optimized Workflow for Liquid Biopsy in a Clinical Setting

A multicenter study was performed to determine an optimal workflow for liquid biopsy in a clinical setting. In total, 549 plasma samples from 234 non-small cell lung cancer (NSCLC) patients were collected. Epidermal Growth Factor Receptor (EGFR) circulating cell-free tumor DNA (ctDNA) mutational ana...

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Bibliographic Details
Main Authors: Laure Sorber, Karen Zwaenepoel, Koen De Winne, Kaat Van Casteren, Elien Augustus, Julie Jacobs, Xiang Hua Zhang, Daniëlla Galdermans, Els De Droogh, Anneke Lefebure, Ann-Marie Morel, Erika Saenen, Frédérique Bustin, Ingel Demedts, Ulrike Himpe, Thierry Pieters, Paul Germonpré, Sofie Derijcke, Koen Deschepper, Jan P. Van Meerbeeck, Christian Rolfo, Patrick Pauwels
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
liquid biopsy
non-small cell lung cancer (NSCLC)
EGFR
ctDNA
ddPCR
Online Access:http://www.mdpi.com/2072-6694/10/9/290

Internet

http://www.mdpi.com/2072-6694/10/9/290

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