Pathological and Prognostic Characterization of Craniopharyngioma Based on the Expression of TrkA, β-Catenin, Cell Cycle Markers, and BRAF V600E Mutation

Pathological and Prognostic Characterization of Craniopharyngioma Based on the Expression of TrkA, β-Catenin, Cell Cycle Markers, and BRAF V600E Mutation

We collected 61 craniopharyngioma (CP) specimens to investigate the expression of TrkA, β-catenin, BRAF gene mutation, and NTRK1 fusion in CP. There were 37 male and 24 female individuals with a median age of 34 years (range, 4–75 years). Histologically, there were 46 cases of adamantinomatous crani...

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Bibliographic Details
Main Authors: Cheng Xu, Songhan Ge, Juanxian Cheng, Huabin Gao, Fenfen Zhang, Anjia Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
Craniopharyngioma
TrkA
β-catenin
cyclin D1
BRAF gene mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.859381/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.859381/full

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