Matrix stiffness regulates osteoclast fate through integrin-dependent mechanotransduction

Osteoclasts ubiquitously participate in bone homeostasis, and their aberration leads to bone diseases, such as osteoporosis. Current clinical strategies by biochemical signaling molecules often perturb innate bone metabolism owing to the uncontrolled management of osteoclasts. Thus, an alternative s...

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Bibliographic Details
Main Authors: Xiaogang Wang, Luli Ji, Jing Wang, Changsheng Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2300107X