A set-theoretic definition of cell types with an algebraic structure on gene regulatory networks and application in annotation of RNA-seq data

A set-theoretic definition of cell types with an algebraic structure on gene regulatory networks and application in annotation of RNA-seq data

Summary: The emergence of single-cell RNA sequencing (RNA-seq) has radically changed the observation of cellular diversity. Although annotations of RNA-seq data require preserved properties among cells of an identity, annotations using conventional methods have not been able to capture universal cha...

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Bibliographic Details
Main Authors: Yuji Okano, Yoshitaka Kase, Hideyuki Okano
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Stem Cell Reports
Subjects:
scRNA-seq
cell type
cellular state
annotation
transcriptome
mathematical model
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671122005112

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http://www.sciencedirect.com/science/article/pii/S2213671122005112

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