SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice

SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice

Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved to variants associated with milder disease. We employed the k18-hACE2 mouse model to study how differences in the course of infection by SARS-CoV-2 variants alpha, delta, and omicron relate to tissue pathology and the...

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Bibliographic Details
Main Authors: Rute Gonçalves, Joana Couto, Pedro Ferreirinha, José Maria Costa, Diogo Silvério, Marta L. Silva, Ana Isabel Fernandes, Pedro Madureira, Nuno L. Alves, Sofia Lamas, Margarida Saraiva
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Pathology
Immunology
Components of the immune system
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000494

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http://www.sciencedirect.com/science/article/pii/S2589004223000494

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