Premature aging in genetic diseases: what conclusions can be drawn for physiological aging

According to current views the major hallmarks of physiological aging may be subdivided into three categories, primary causes of cellular damage (genomic instability, telomere attrition, loss of proteostasis, epigenetic alterations and compromised macroautophagy), antagonistic hallmarks that represe...

Full description

Bibliographic Details
Main Authors: Filip Milosic, Markus Hengstschläger, Selma Osmanagic-Myers
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2023.1327833/full