Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

Polyamines are small polycationic alkylamines involved in many fundamental cellular processes, including cell proliferation, survival, and protection from oxidative stress. Polyamine homeostasis is tightly regulated through coordinated biosynthesis, catabolism, and transport. Due to their continual...

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Bibliographic Details
Main Authors: Cassandra E. Holbert, Jackson R. Foley, Ao Yu, Tracy Murray Stewart, Otto Phanstiel, David Oupicky, Robert A. Casero
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Medical Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3271/10/3/44