The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

Objectives: This study combines two innovative mouse models in a major gene discovery project to assess the influence of host genetics on asbestos related disease (ARD). Conventional genetics studies provided evidence that some susceptibility to mesothelioma is genetic. However, the identification o...

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Bibliographic Details
Main Authors: Scott A. Fisher, Kimberley Patrick, Tracy Hoang, Elly Marcq, Kiarash Behrouzfar, Sylvia Young, Timothy J. Miller, Bruce W. S. Robinson, Raphael Bueno, Anna K. Nowak, W. Joost Lesterhuis, Grant Morahan, Richard A. Lake
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Toxicology
Subjects:
mesothelioma
collaborative cross
MexTAg
asbestos related disease
host genetics
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1373003/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2024.1373003/full

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