Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray

Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray

Summary: Here, we present a protocol for deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray. We describe steps for utilizing NMF-defined group 3/group 4 metagenes to calculate a continuum score between 0 and 1 that can...

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Bibliographic Details
Main Authors: James P.R. Hacking, Dean Thompson, Edward C. Schwalbe, Steven C. Clifford, Daniel Williamson
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:STAR Protocols
Subjects:
Bioinformatics
Sequence analysis
Cancer
Sequencing
RNAseq
Molecular Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723004768

Internet

http://www.sciencedirect.com/science/article/pii/S2666166723004768

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