Sensitive spectrophotometric assay of simvastatin in pharmaceuticals using permanganate

Two simple, sensitive, selective and inexpensive spectrophotometric methods are described for the determination of simvastatin (SMT) in bulk drug and in tablets using permanganate as the oxidimetric reagent. In method A, SMT is treated with a measured excess of permanganate in acetic acid medium and...

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Bibliographic Details
Main Authors: Kalsang Tharpa, Kanakapura Basavaiah, Nagaraju Rajedraprasad, Kanakapura Basavaiah Vinay, Salmara Ganeshbhat Hiriyanna
Format: Article
Language:English
Published: Universidade de São Paulo 2010-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000100010