Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.
The "thrifty genotype" hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low calorie/high exercise lifestyle. However, identification of the gene varian...
Glavni autori: | Desmond D Campbell, Maria V Parra, Constanza Duque, Natalia Gallego, Liliana Franco, Arti Tandon, Tábita Hünemeier, Cátira Bortolini, Alberto Villegas, Gabriel Bedoya, Mark I McCarthy, Alkes Price, David Reich, Andrés Ruiz-Linares |
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Format: | Članak |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2012-01-01
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Serija: | PLoS ONE |
Online pristup: | http://europepmc.org/articles/PMC3328483?pdf=render |
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Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.
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