Role of mitochondrial translation in remodeling of energy metabolism in ER/PR(+) breast cancer

Role of mitochondrial translation in remodeling of energy metabolism in ER/PR(+) breast cancer

Remodeling of mitochondrial energy metabolism is essential for the survival of tumor cells in limited nutrient availability and hypoxic conditions. Defects in oxidative phosphorylation (OXPHOS) and mitochondrial biogenesis also cause a switch in energy metabolism from oxidative to aerobic glycolysis...

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Bibliographic Details
Main Authors: Emine C. Koc, Fatih C. Koc, Funda Kartal, Maria Tirona, Hasan Koc
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
mitochondrial translation
mitochondrial ribosomal proteins (MRPs)
oxidative phosphorylation (OXPHOS)
breast cancer
ER/PR(+)
luminal A
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.897207/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.897207/full

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