Sculpting Rupture‐Free Nuclear Shapes in Fibrous Environments

Sculpting Rupture‐Free Nuclear Shapes in Fibrous Environments

Abstract Cytoskeleton‐mediated force transmission regulates nucleus morphology. How nuclei shaping occurs in fibrous in vivo environments remains poorly understood. Here suspended nanofiber networks of precisely tunable (nm–µm) diameters are used to quantify nucleus plasticity in fibrous environment...

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Bibliographic Details
Main Authors: Aniket Jana, Avery Tran, Amritpal Gill, Alexander Kiepas, Rakesh K. Kapania, Konstantinos Konstantopoulos, Amrinder S. Nain
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Advanced Science
Subjects:
cell forces
cell spreading
cell‐cytoskeleton
extracellular matrices
nanofibers
nucleus shapes
Online Access:https://doi.org/10.1002/advs.202203011

Internet

https://doi.org/10.1002/advs.202203011

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