A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution

A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution

During the resolution of inflammation, macrophages engulf apoptotic polymorphonuclear cells (PMN) and can accumulate large numbers of their corpses. Here, we report that resolution phase macrophages acquire the neutrophil-derived glycoprotein lactoferrin (Lf) and fragments thereof in vivo and ex viv...

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Bibliographic Details
Main Authors: Aviv Lutaty, Soaad Soboh, Sagie Schif-Zuck, Orly Zeituni-Timor, Ran Rostoker, Malgorzata J. Podolska, Christine Schauer, Martin Herrmann, Luis E. Muñoz, Amiram Ariel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
resolution of inflammation
lactoferrin
macrophages
efferocytosis
NETosis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00644/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00644/full

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