Thymoquinone-Enriched Naringenin-Loaded Nanostructured Lipid Carrier for Brain Delivery via Nasal Route: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Treatment of Depression

Thymoquinone-Enriched Naringenin-Loaded Nanostructured Lipid Carrier for Brain Delivery via Nasal Route: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Treatment of Depression

In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured lipid carrier (NLC) was developed and delivered via the nasal route for depression. Thymoquinone (TQ) oil was used as the liquid lipid and provided synergistic effects. A TQ- and NGN-enriched NLC was developed vi...

Full description

Bibliographic Details
Main Authors: Farheen Fatima Qizilbash, Muhammad Usama Ashhar, Ameeduzzafar Zafar, Zufika Qamar, Annu, Javed Ali, Sanjula Baboota, Mohammed M. Ghoneim, Sultan Alshehri, Asgar Ali
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
naringenin
nanostructured lipid carrier
intranasal delivery
central composite rotatable design
depression
Online Access:https://www.mdpi.com/1999-4923/14/3/656

Internet

https://www.mdpi.com/1999-4923/14/3/656

Similar Items