Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing

Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing

New methods of tumor ablation have shown exciting efficacy in pre-clinical models but often demonstrate limited success in the clinic. Due to a lack of quality or quantity in primary malignant tissue specimens, therapeutic development and optimization studies are typically conducted on healthy tissu...

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Bibliographic Details
Main Authors: Rebecca M. Brock, Natalie Beitel-White, Sheryl Coutermarsh-Ott, Douglas J. Grider, Melvin F. Lorenzo, Veronica M. Ringel-Scaia, Navid Manuchehrabadi, Robert C. G. Martin, Rafael V. Davalos, Irving C. Allen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
irreversible electroporation
PDX
conductivity
inflammation
pancreatic cancer
ablation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00843/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00843/full

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