Necrotizing pancreatitis: challenges and solutions
Victoria A Bendersky,1 Mohan K Mallipeddi,2 Alexander Perez,2 Theodore N Pappas,2 1School of Medicine, 2Department of Surgery, Duke University, Durham, NC, USA Abstract: Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2016-10-01
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| Series: | Clinical and Experimental Gastroenterology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/necrotizing-pancreatitis-challenges-and-solutions-peer-reviewed-article-CEG |
| _version_ | 1831774766988525568 |
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| author | Bendersky VA Mallipeddi MK Perez A Pappas TN |
| author_facet | Bendersky VA Mallipeddi MK Perez A Pappas TN |
| author_sort | Bendersky VA |
| collection | DOAJ |
| description | Victoria A Bendersky,1 Mohan K Mallipeddi,2 Alexander Perez,2 Theodore N Pappas,2 1School of Medicine, 2Department of Surgery, Duke University, Durham, NC, USA Abstract: Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications. Keywords: necrotizing pancreatitis, pancreatic necrosectomy, VARD, pancreatic debridement, pancreatic collections |
| first_indexed | 2024-12-22T09:00:20Z |
| format | Article |
| id | doaj.art-3d4b4eb56ae048219444f6c80bd1b571 |
| institution | Directory Open Access Journal |
| issn | 1178-7023 |
| language | English |
| last_indexed | 2024-12-22T09:00:20Z |
| publishDate | 2016-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical and Experimental Gastroenterology |
| spelling | doaj.art-3d4b4eb56ae048219444f6c80bd1b5712022-12-21T18:31:43ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232016-10-01Volume 934535029738Necrotizing pancreatitis: challenges and solutionsBendersky VAMallipeddi MKPerez APappas TNVictoria A Bendersky,1 Mohan K Mallipeddi,2 Alexander Perez,2 Theodore N Pappas,2 1School of Medicine, 2Department of Surgery, Duke University, Durham, NC, USA Abstract: Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications. Keywords: necrotizing pancreatitis, pancreatic necrosectomy, VARD, pancreatic debridement, pancreatic collectionshttps://www.dovepress.com/necrotizing-pancreatitis-challenges-and-solutions-peer-reviewed-article-CEGNecrotizing PancreatitisPancreatic NecrosectomyVARDPancreatic DebridementPancreatic Collections |
| spellingShingle | Bendersky VA Mallipeddi MK Perez A Pappas TN Necrotizing pancreatitis: challenges and solutions Clinical and Experimental Gastroenterology Necrotizing Pancreatitis Pancreatic Necrosectomy VARD Pancreatic Debridement Pancreatic Collections |
| title | Necrotizing pancreatitis: challenges and solutions |
| title_full | Necrotizing pancreatitis: challenges and solutions |
| title_fullStr | Necrotizing pancreatitis: challenges and solutions |
| title_full_unstemmed | Necrotizing pancreatitis: challenges and solutions |
| title_short | Necrotizing pancreatitis: challenges and solutions |
| title_sort | necrotizing pancreatitis challenges and solutions |
| topic | Necrotizing Pancreatitis Pancreatic Necrosectomy VARD Pancreatic Debridement Pancreatic Collections |
| url | https://www.dovepress.com/necrotizing-pancreatitis-challenges-and-solutions-peer-reviewed-article-CEG |
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