Assessment of Single Cell RNA-Seq Normalization Methods

Assessment of Single Cell RNA-Seq Normalization Methods

We have assessed the performance of seven normalization methods for single cell RNA-seq using data generated from dilution of RNA samples. Our analyses showed that methods considering spike-in External RNA Control Consortium (ERCC) RNA molecules significantly outperformed those not considering ERCCs...

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Bibliographic Details
Main Authors: Bo Ding, Lina Zheng, Wei Wang
Format: Article
Language:English
Published: Oxford University Press 2017-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
normalization
scRNA
statistical index
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.040683

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.040683

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