Brain-Type Glycogen Phosphorylase Is Crucial for Astrocytic Glycogen Accumulation in Chronic Social Defeat Stress-Induced Depression in Mice

Brain-Type Glycogen Phosphorylase Is Crucial for Astrocytic Glycogen Accumulation in Chronic Social Defeat Stress-Induced Depression in Mice

Astrocytic glycogen plays an important role in brain energy metabolism. However, the contribution of glycogen metabolism to stress-induced depression remains unclear. Chronic social defeat stress was used to induce depression-like behaviors in mice, assessed with behavioral tests. Glycogen concentra...

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Bibliographic Details
Main Authors: Yuanyuan Zhu, Ze Fan, Qiuying Zhao, Jiaqi Li, Guohong Cai, Rui Wang, Yi Liang, Naining Lu, Junjun Kang, Danlei Luo, Huiren Tao, Yan Li, Jing Huang, Shengxi Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
glycogen
astrocyte
medial prefrontal cortex
brain type glycogen phosphorylase
depression
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.819440/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.819440/full

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