Zearalenone and ß-Zearalenol But Not Their Glucosides Inhibit Heat Shock Protein 90 ATPase Activity

The mycotoxin zearalenone (ZEN) is produced by many plant pathogenic Fusarium species. It is well known for its estrogenic activity in humans and animals, but whether ZEN has a role in plant–pathogen interaction and which process it is targeting in planta was so far unclear. We found that treatment...

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Bibliographic Details
Main Authors: Juan Antonio Torres Acosta, Herbert Michlmayr, Mehrdad Shams, Wolfgang Schweiger, Gerlinde Wiesenberger, Rudolf Mitterbauer, Ulrike Werner, David Merz, Marie-Theres Hauser, Christian Hametner, Elisabeth Varga, Rudolf Krska, Franz Berthiller, Gerhard Adam
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01160/full