Pressure Adaptations in Deep-Sea <i>Moritella</i> Dihydrofolate Reductases: Compressibility versus Stability
Proteins from “pressure-loving” piezophiles appear to adapt by greater compressibility via larger total cavity volume. However, larger cavities in proteins have been associated with lower unfolding pressures. Here, dihydrofolate reductase (DHFR) from a moderate piezophile <i>Moritella profunda...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/10/11/1211 |