Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein–protein interfaces

Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein–protein interfaces

Abstract Background Protein–protein interactions (PPIs) are conveyed through binding interfaces or surface patches on proteins that become buried upon binding. Structural and biophysical analysis of many protein–protein interfaces revealed certain unique features of these surfaces that determine the...

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Bibliographic Details
Main Authors: Sagara N. S. Gurusinghe, Julia M. Shifman
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Bioinformatics
Subjects:
Protein–protein interactions
Cold spots
Cavities
Binding interface
Binding affinity
Online Access:https://doi.org/10.1186/s12859-024-05796-5

Internet

https://doi.org/10.1186/s12859-024-05796-5

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