Cold Case of Thrombolysis: Cold Recombinant Tissue Plasminogen Activator Confers Enhanced Neuroprotection in Experimental Stroke

Cold Case of Thrombolysis: Cold Recombinant Tissue Plasminogen Activator Confers Enhanced Neuroprotection in Experimental Stroke

Background Thrombolysis and endovascular thrombectomy are the primary treatment for ischemic stroke. However, due to the limited time window and the occurrence of adverse effects, only a small number of patients can genuinely benefit from recanalization. Intraarterial injection of rtPA (recombinant...

Full description

Bibliographic Details
Main Authors: Yuyou Huang, Shanshan Gu, Ziping Han, Zhenghong Yang, Liyuan Zhong, Lingzi Li, Rongliang Wang, Feng Yan, Yumin Luo, Cesario Borlongan, Jie Lu
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
blood–brain barrier
hypothermia
inflammation
ischemic stroke
middle cerebral artery occlusion
tissue plasminogen activator
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.029817

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.123.029817

Similar Items