Phylodynamic theory of persistence, extinction and speciation of rapidly adapting pathogens

Rapidly evolving pathogens like influenza viruses can persist by changing their antigenic properties fast enough to evade the adaptive immunity, yet they rarely split into diverging lineages. By mapping the multi-strain Susceptible-Infected-Recovered model onto the traveling wave model of adapting p...

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Bibliographic Details
Main Authors: Le Yan, Richard A Neher, Boris I Shraiman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/44205