Lipophilicity and Pharmacokinetic Properties of New Anticancer Dipyridothiazine with 1,2,3-Triazole Substituents

Lipophilicity and Pharmacokinetic Properties of New Anticancer Dipyridothiazine with 1,2,3-Triazole Substituents

The lipophilicity parameters (log<i>P<sub>calcd</sub></i>, <i>R<sub>M</sub></i><sub>0</sub> and log<i>P<sub>TLC</sub></i>) of 10 new active anticancer dipirydothiazines with a 1,2,3-triazole ring were determined theo...

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Bibliographic Details
Main Authors: Beata Morak-Młodawska, Małgorzata Jeleń
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
lipophilicity
RP-TLC, ADME properties
dipyridothiazine
1,2,3-triazole
anticancer activity
Lipinski’s, Ghose’s, Veber’s rules
Online Access:https://www.mdpi.com/1420-3049/27/4/1253

Internet

https://www.mdpi.com/1420-3049/27/4/1253

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