Clinical significance and research progress of DNA methylation in glioma
Glioma has a specific CpG island methylator phenotype (G⁃CIMP), which is closely related to isocitrate dehydrogenase (IDH) mutation. A hypermutation is present at recurrence in temozolomide⁃treated gliomas, and O6⁃methylguanine⁃DNA methyltransferase (MGMT) promoter methylation levels can help predic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2022-09-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2569 |