p63, a key regulator of Ago2, links to the microRNA-144 cluster

p63, a key regulator of Ago2, links to the microRNA-144 cluster

Abstract As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of the tumor suppressor p53. p63 isoforms play a criti...

Full description

Bibliographic Details
Main Authors: Benfan Wang, H. Helena Wu, Yasser Abuetabh, Sarah Leng, Sandra T. Davidge, Elsa R. Flores, David D. Eisenstat, Roger Leng
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04854-1

Internet

https://doi.org/10.1038/s41419-022-04854-1

Similar Items