Pretransfusion Testing and Daratumumab: Assessing Interference Risks and Developing Solutions

Pretransfusion Testing and Daratumumab: Assessing Interference Risks and Developing Solutions

Daratumumab is a monoclonal antibody; anti-CD38 is used for the treatment of multiple myeloma and other hematological disorders. Daratumumab, binds to CD 38 on red blood cells (RBCs), interfering with pretransfusion testing. This interference can lead to cross match incompatibility and panreactive i...

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Bibliographic Details
Main Authors: Saroj Rajput, Tathagata Chatterjee, Rahul Bhargava, Sanjay Rai
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-05-01
Series:Global Journal of Transfusion Medicine
Subjects:
daratumumab
dithiothreitol
pretransfusion testing
Online Access:https://journals.lww.com/10.4103/gjtm.gjtm_52_23

Internet

https://journals.lww.com/10.4103/gjtm.gjtm_52_23

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