Identification of an early survival prognostic gene signature for localized osteosarcoma patients

Abstract Osteosarcoma is the most prevalent bone tumor in pediatric patients. Neoadjuvant chemotherapy has improved osteosarcoma patient survival, however the 5-year survival rate for localized osteosarcoma is 75% with a 30–50% recurrence rate. We, therefore, sought to identify a prognostic gene sig...

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Bibliographic Details
Main Authors: Tajhal D. Patel, Sandra L. Grimm, Rupa S. Kanchi, Tanmay Gandhi, Amrit Koirala, Jason T. Yustein, Cristian Coarfa
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57527-8