JumonjiC demethylase inhibitors show potential for targeting chemotherapy-resistant lung cancers

JumonjiC demethylase inhibitors show potential for targeting chemotherapy-resistant lung cancers

Resistance to standard taxane-platin chemotherapy and tumor relapse are a major challenge in the treatment of non-small cell lung cancers (NSCLC). Our recent study identified JumonjiC demethylase inhibitors as a highly potent therapeutic strategy for targeting chemoresistant tumors and for preventin...

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Bibliographic Details
Main Authors: Maithili P. Dalvi, Elisabeth D. Martinez
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:Molecular & Cellular Oncology
Subjects:
drug resistance
jmjc demethylases
jumonji inhibitors
kdm
non-small cell lung cancer
standard chemotherapy
taxane-platin
Online Access:http://dx.doi.org/10.1080/23723556.2017.1345352

Internet

http://dx.doi.org/10.1080/23723556.2017.1345352

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