Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy

Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy

Cerebral amyloid angiopathy (CAA), a common comorbidity of Alzheimer’s disease (AD), is a cerebral small vessel disease (CSVD) characterized by deposition of fibrillar amyloid β (Aβ) in blood vessels of the brain and promotes neuroinflammation and vascular cognitive impairment and dementia (VCID). H...

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Bibliographic Details
Main Authors: Aleksandra Stanisavljevic, Joseph M. Schrader, Xiaoyue Zhu, Jennifer M. Mattar, Ashley Hanks, Feng Xu, Mark Majchrzak, John K. Robinson, William E. Van Nostrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neuroscience
Subjects:
cerebral amyloid angiopathy
hypertension
comorbidity
transgenic rat
cerebral microbleeds
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.811371/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.811371/full

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