PIK3CA mutations in breast cancer with low HER2 / neu expression

Introduction. Disturbances in the PI3K-dependent (PI3K – phosphoinositide 3‑kinase) cascade are characteristic of all types of breast cancer. In particular, 30–40 % of patients with advanced / metastatic hormone-positive HER2‑negative (HER2 – human epidermal growth factor receptor 2) breast cancer c...

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Bibliographic Details
Main Authors: I. A. Pavlenko, P. E. Povilaitite, V. Yu. Kaciyaev, N. S. Makarevich, A. V. Petrov
Format: Article
Language:Russian
Published: ABV-press 2022-12-01
Series:Успехи молекулярной онкологии
Subjects:
Online Access:https://umo.abvpress.ru/jour/article/view/480