Sequence variants contributing to dysregulated inflammatory responses across keratoconic cone surface in adolescent patients with keratoconus

Sequence variants contributing to dysregulated inflammatory responses across keratoconic cone surface in adolescent patients with keratoconus

BackgroundKeratoconus (KTCN) is the most common corneal ectasia resulting in a conical shape of the cornea. Here, genomic variation in the corneal epithelium (CE) across the keratoconic cone surface in patients with KTCN and its relevance in the functioning of the immune system were assessed.Methods...

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Bibliographic Details
Main Authors: Katarzyna Jaskiewicz, Magdalena Maleszka-Kurpiel, Michał Kabza, Justyna A. Karolak, Marzena Gajecka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
cornea
corneal epithelium
inflammation
non-coding sequence variation
whole genome
WGS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197054/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197054/full

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