Senescence drives non-cell autonomous tumorigenesis in the pituitary gland

Novel detrimental functions of senescent cells have been recently uncovered in the context of cancer development and progression, which they mainly exert through the secretion of several pro-tumorigenic factors. Here we discuss how cellular senescence and its secretory phenotype can be involved in t...

Full description

Bibliographic Details
Main Authors: Jose Mario Gonzalez-Meljem, Juan Pedro Martinez-Barbera
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2018.1435180