MicroRNA modulated networks of adaptive and innate immune response in pancreatic ductal adenocarcinoma.

Despite progress in treatment strategies, only ~24% of pancreatic ductal adenocarcinoma (PDAC) patients survive >1 year. Our goal was to elucidate deregulated pathways modulated by microRNAs (miRNAs) in PDAC and Vater ampulla (AMP) cancers. Global miRNA expression was identified in 19 PDAC, 6 AMP...

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Main Authors: Tainara F Felix, Rainer M Lopez Lapa, Márcio de Carvalho, Natália Bertoni, Tomas Tokar, Rogério A Oliveira, Maria A M Rodrigues, Cláudia N Hasimoto, Walmar K Oliveira, Leonardo Pelafsky, César T Spadella, Juan C Llanos, Giovanni F Silva, Wan L Lam, Silvia Regina Rogatto, Luciana Schultz Amorim, Sandra A Drigo, Robson F Carvalho, Patricia P Reis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217421