Intratracheal instillation for the testing of pulmonary toxicity in mice—Effects of instillation devices and feed type on inflammation

Abstract Background Inhalation exposure is the gold standard when assessing pulmonary toxicity. However, it typically requires substantial amounts of test material. Intratracheal instillation is an alternative administration technique, where the test substance is suspended in a liquid vehicle and de...

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Bibliographic Details
Main Authors: Niels Hadrup, Michael Guldbrandsen, Eva Terrida, Katja M. S. Bendtsen, Karin S. Hougaard, Nicklas R. Jacobsen, Ulla Vogel
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Animal Models and Experimental Medicine
Subjects:
Online Access:https://doi.org/10.1002/ame2.12503