Sphingosine 1-phosphate receptor 2 promotes the onset and progression of non-alcoholic fatty liver disease-related hepatocellular carcinoma through the PI3K/AKT/mTOR pathway

Abstract Purpose Recent studies have revealed an increase in the incidence rate of non-alcoholic fatty liver disease-related hepatocellular carcinoma (NAFLD-HCC). Furthermore, the association of Sphingosine 1-phosphate receptor 2 (S1PR2) with various types of tumours is identified, and the metabolis...

Full description

Bibliographic Details
Main Authors: Ganggang Wang, Xin Zhang, Zhijie Zhou, Chao Song, Wenzhi Jin, Hao Zhang, Weixin Wu, Yong Yi, Hengguan Cui, Ping Zhang, Xinyu Liu, Weiqiang Xu, Xiaowei Shen, Weixing Shen, Xiaoliang Wang
Format: Article
Language:English
Published: Springer 2023-01-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-023-00611-8