Relation of α<sub>2</sub>-Antiplasmin Genotype and Genetic Determinants of Fibrinogen Synthesis and Fibrin Clot Formation with Vascular Endothelial Growth Factor Level in Axial Spondyloarthritis

Relation of α<sub>2</sub>-Antiplasmin Genotype and Genetic Determinants of Fibrinogen Synthesis and Fibrin Clot Formation with Vascular Endothelial Growth Factor Level in Axial Spondyloarthritis

Objective: Coagulation and fibrinolysis are interrelated with the expression of vascular endothelial growth factor (VEGF), which frequently is increased in axial spondyloarthritis (axSpA). We tested whether (i) α<sub>2</sub>-antiplasmin (A2AP) Arg6Trp, (ii) fibrinogen, factor XIII A-subu...

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Bibliographic Details
Main Authors: Berthold Hoppe, Christian Schwedler, Hildrun Haibel, Maryna Verba, Fabian Proft, Mikhail Protopopov, Hans-Gert Heuft, Valeria Rios Rodriguez, Anke Edelmann, Martin Rudwaleit, Joachim Sieper, Denis Poddubnyy
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
fibrinolysis
α<sub>2</sub>-antiplasmin
fibrinogen
factor XIII
spondyloarthritis
vascular endothelial growth factor
Online Access:https://www.mdpi.com/1422-0067/21/24/9383

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https://www.mdpi.com/1422-0067/21/24/9383

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