Alterations in Mitochondrial Morphology and Quality Control in Primary Mouse Lung Microvascular Endothelial Cells and Human Dermal Fibroblasts under Hyperglycemic Conditions

Alterations in Mitochondrial Morphology and Quality Control in Primary Mouse Lung Microvascular Endothelial Cells and Human Dermal Fibroblasts under Hyperglycemic Conditions

The effect of hyperglycemia on the morphology of individual mitochondria and the state of the mitochondrial network in primary mouse lung microvascular endotheliocytes and human dermal fibroblasts has been investigated. The cells were exposed to high (30 mM) and low (5.5 mM) glucose concentrations f...

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Bibliographic Details
Main Authors: Natalia V. Belosludtseva, Dmitriy A. Serov, Vlada S. Starinets, Nikita V. Penkov, Konstantin N. Belosludtsev
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic hyperglycemia
mitochondrial dysfunction
mitochondrial morphology
mitochondrial dynamics
mitophagy
mitochondrial biogenesis
Online Access:https://www.mdpi.com/1422-0067/24/15/12485

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https://www.mdpi.com/1422-0067/24/15/12485

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