A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

Abstract Background Acute type A aortic dissection (AAAD) is a devastating disease. Human aortic smooth muscle cells (HASMCs) exhibit decreased proliferation and increased apoptosis, and integrin α5β1 and FAK are important proangiogenic factors involved in regulating angiogenesis. The aim of this st...

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Bibliographic Details
Main Authors: Mingming Xue, Lingyu Xing, Yilin Yang, Mian Shao, Fengqing Liao, Feixiang Xu, Yumei Chen, Sheng Wang, Bin Chen, Chenling Yao, Guorong Gu, Chaoyang Tong
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Acute type a aortic dissection
Integrin α5β
Human aortic smooth cell
Apoptosis
Online Access:https://doi.org/10.1186/s12872-024-03778-2

Internet

https://doi.org/10.1186/s12872-024-03778-2

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