Glycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2.

The Sulfs are a family of endosulfatases that selectively modify the 6O-sulfation state of cell-surface heparan sulfate (HS) molecules. Sulfs serve as modulators of cell-signaling events because the changes they induce alter the cell surface co-receptor functions of HS chains. A variety of studies h...

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Bibliographic Details
Main Authors: Gregory O Staples, Xiaofeng Shi, Joseph Zaia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3035651?pdf=render