Functional alterations in large-scale resting-state networks of amyotrophic lateral sclerosis: A multi-site study across Canada and the United States.

Functional alterations in large-scale resting-state networks of amyotrophic lateral sclerosis: A multi-site study across Canada and the United States.

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Amyotrophic lateral sclerosis (ALS) is a multisystem neurodegenerative disorder characterized by progressive degeneration of upper motor neurons and lower motor neurons, and frontotemporal regions resulting in impaired bulbar, limb, and cognitive function. Magnetic resonance imaging studies have rep...

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Bibliographic Details
Main Authors: Komal Bharti, Simon J Graham, Michael Benatar, Hannah Briemberg, Sneha Chenji, Nicolas Dupré, Annie Dionne, Richard Frayne, Angela Genge, Lawrence Korngut, Collin Luk, Lorne Zinman, Sanjay Kalra, Canadian ALS Neuroimaging Consortium (CALSNIC)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0269154

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https://doi.org/10.1371/journal.pone.0269154

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