Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation

Summary: Chondrolectin (Chodl) is needed for motor axon extension in zebrafish and is dysregulated in mouse models of spinal muscular atrophy (SMA). However, the mechanistic basis of Chodl function is not known. Here, we use Chodl-deficient zebrafish and mouse mutants to show that the absence of Cho...

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Bibliographic Details
Main Authors: Ana-Maria Oprişoreanu, Hannah L. Smith, Sukrat Arya, Richard Webster, Zhen Zhong, Daniel Wehner, Marcos J. Cardozo, Thomas Becker, Kevin Talbot, Catherina G. Becker
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719312215