Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction.

Glucocorticoids production is increased in many pathological conditions that are associated with muscle loss, but their role in causing muscle wasting is not fully understood. We have demonstrated a new mechanism of glucocorticoid-induced muscle atrophy: Dexamethasone (Dex) suppresses satellite cell...

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Bibliographic Details
Main Authors: Yanjun Dong, Jenny S Pan, Liping Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596298?pdf=render