Transporter annotations are holding up progress in metabolic modeling

Mechanistic, constraint-based models of microbial isolates or communities are a staple in the metabolic analysis toolbox, but predictions about microbe-microbe and microbe-environment interactions are only as good as the accuracy of transporter annotations. A number of hurdles stand in the way of co...

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Bibliographic Details
Main Authors: John Casey, Brian Bennion, Patrik D’haeseleer, Jeffrey Kimbrel, Gianna Marschmann, Ali Navid
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Systems Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2024.1394084/full